This function performs statistical testing for differential
enrichment using plaid
Usage
fc_ttest(fc, G, sort.by = "pvalue")
Arguments
- fc
Vector of logFC values
- G
Sparse matrix of gene sets. Non-zero entry indicates
gene/feature is part of gene sets. Features on rows, gene sets on
columns.
- sort.by
Column name to sort results by ("pvalue", "gsetFC", or "none")
Value
Data frame with columns: gsetFC (gene set fold change),
pvalue (p-value from one-sample t-test), and qvalue (FDR-adjusted p-value).
