This function performs statistical testing for differential
enrichment using plaid
Usage
fc_ztest(fc, G, zmat = FALSE, alpha = 0.5)
Arguments
- fc
Vector of logFC values
- G
Sparse matrix of gene sets. Non-zero entry indicates
gene/feature is part of gene sets. Features on rows, gene sets on
columns.
- zmat
Logical indicating to return z-matrix
- alpha
Scalar weight for SD estimation. Default 0.5.
Value
List with element: z_statistic (z-statistic from one-sample z-test),
p_value (p-value from one-sample z-test), and zmat (z-matrix).
